Carisoprodol (trade names embody Soma, Somadril, Carisoma, Carisoprodol Watson, Listaflex, Somacid, Vanadom) is a muscle relaxant from carbamic acid esters pharmacological group. This treatment is indicated along with rest and physical therapy to alleviate musculoskeletal pain, skeletal muscle spasms, stiffness, muscle accidents, pressure, sprain, acute again pain, discomfort related to short-term, painful musculoskeletal conditions, and for different medical purposes. It can also be widely off-label used as leisure drug. Carisoprodol could also be prescribed alone for monotherapy or in combos with different drugs, such as psycholeptics.
Clinical presentation </h2
Overdosage of Carisoprodol (Soma) tablets commonly produces CNS melancholy. Death, coma, respiratory despair, hypotension, seizures, delirium, hallucinations, dystonic reactions, nystagmus, blurred vision, mydriasis, euphoria, muscular incoordination, rigidity, and/or headache have been reported with Soma overdosage. Serotonin syndrome has been reported with carisoprodol intoxication. Many of the carisoprodol overdoses have occurred within the setting of a quantity of drug overdoses (including medication of abuse, illegal drugs, and alcohol). The results of an overdose of this treatment and other CNS depressants (e.g., alcohol, benzodiazepines, opioids, tricyclic antidepressants) could be additive even when one of the medication has been taken in the recommended dosage. Fatal unintended and non-accidental overdoses of SOMA have been reported alone or together with CNS depressants.
Treatment of overdosage
Basic life help measures ought to be instituted as dictated by the medical presentation of the Soma overdose. Vomiting should not be induced because of the danger of CNS and respiratory despair, and subsequent aspiration. Circulatory support must be administered with quantity infusion and vasopressor agents if wanted. Seizures ought to be handled with intravenous benzodiazepines and the reoccurrence of seizures could additionally be handled with phenobarbital. In cases of severe CNS melancholy, airway protective reflexes could also be compromised and tracheal intubation should be thought-about for airway protection and respiratory support.
For decontamination in cases of extreme toxicity, activated charcoal must be considered in a hospital setting in patients with giant overdoses who present early and are not demonstrating CNS melancholy and may shield their airway.
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